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  • 产品名称:anti-HIV-1Tatantibody

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  • 产品厂商:DIATHEVA
  • 产品价格:371456
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简单介绍:
anti-HIV-1TatAntibody
详情介绍:
Immunogen Recombinant purified HIV-1 tat protein Clade B expressed in E. coli
Specificity Tat protein clade A and B, GSTTat fusion protein
Characteristics The HIV-1 regulatory protein tat is considered an attractive target for the development of a multicomponent vaccine against HIV-1 infection. The protein is well conserved among different isolates and thus may be less susceptible to mutation leading to the production of escape virus variants. Tat is produced early after infection and it's essential for virus replication and infectivity. Tat protein is also immunogenic and antibodies (Ab) against tat have been correlated with delayed disease progression and may exert protective effects inhibiting HIV replication. Moreover, Tat is efficiently taken up by monocyte-derived dendritic cells, promoting their maturation. Finally, murine vaccination with a biologically active tat protein has been shown to be safe and immunogenic.
Purification Polyclonal immunoglobulins purified by affinity chromatography.
Alternative Name HIV1 Tat
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Buffer Supplied in 100 mM sodium citrate, 50 mM Tris and 0.05 % v/v glycerol
Storage 4 °C