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  • 产品名称：anti-HIV-1Vif(N-Term)antibody

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  • 产品厂商：DIATHEVA
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简单介绍：
anti-HIV-1Vif(N-Term)antibody
详情介绍：
Immunogen Bacterially expressed, hexahistidine amino-terminal tagged HIV-1 VIF protein (clade B, HXB-3 isolate)
Clone 319
Characteristics Vif (Virion infectivity factor) is a 23- kDa phosphoprotein that is expressed late in the retroviral life cycle. Vif is absolutely essential for a productive HIV-1 infection in primary CD4 T cells, macrophages and certain T-cell lines (eg, H9 and CEM). Vif induces productive viral replication by inactivating the host cell antiviral restriction factor APOBEC3G (A3G). A3G and related cytidine deaminases of the APOBEC3 family are potent inhibitors of many retroviruses, including HIV-1.
Purification Antibodies are purified from supernatants of hybridoma cell cultures by affinity chromatography.
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Buffer Supplied in 100 mM sodium citrate, 50 mM Tris and 0.05 % v/v glycerol
Storage 4 °C