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  • 产品名称：Thrombopoietin(THPO)(Active)Protein

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  • 产品厂商：SXBIO
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简单介绍：
Thrombopoietin(THPO)(Active)Protein
详情介绍：
Sequence SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF
Characteristics Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human MO7e cells is less than 1.0 ng/mL, corresponding to a specific activity of ＞ 1.0 x 106 IU/mg.
Purity >95 % as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
Synonyms: C-mpl ligand, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, MGDF, Myeloproliferative leukemia virus oncogene ligand
Molecular Weight 18.7 kDa
UniProt P40226
Pathways JAK-STAT Signaling, Hormone Activity
Restrictions For Research Use only
Format Lyophilized
Buffer PBS, pH 7.4, with 5 % Trehalose
Storage -20 °C