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  • 产品名称：Chemokine(C-CMotif)Ligand19(CCL19)(Active)Protein

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  • 产品厂商：SXBIO
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简单介绍：
Chemokine(C-CMotif)Ligand19(CCL19)(Active)Protein
详情介绍：
Sequence GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS
Characteristics Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human mature dendritic cells is in a concentration range of 10-100 ng/mL.
Purity >97?% as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Synonyms: Epstein-Barr virus-induced molecule 1 ligand chemokine, ELC, Small-inducible cytokine A19
Molecular Weight 9.2 kDa
UniProt O70460
Pathways Positive Regulation of Immune Effector Process
Restrictions For Research Use only
Format Lyophilized
Buffer PBS,?pH 7.4
Storage -20 °C