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  • 产品名称：serpinPeptidaseInhibitor,CladeI(neuroserpin),Member1(SERPINI1)(Active)Protein

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  • 产品厂商：SXBIO
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简单介绍：
serpinPeptidaseInhibitor,CladeI(neuroserpin),Member1(SERPINI1)(Active)Protein
详情介绍：
Sequence TGATFPEEAI ADLSVNMYNR LRATGEDENI LFSPLSIALA MGMMELGAQG STQKEIRHSM GYDSLKNGEE FSFLKEFSNM VTAKESQYVM KIANSLFVQN GFHVNEEFLQ MMKKYFNAAV NHVDFSQNVA VANYINKWVE NNTNNLVKDL VSPRDFDAAT YLALINAVYF KGNWKSQFRP ENTRTFSFTK DDESEVQIPM MYQQGEFYYG EFSDGSNEAG GIYQVLEIPY EGDEISMMLV LSRQEVPLAT LEPLVKAQLV EEWANSVKKQ KVEVYLPRFT VEQEIDLKDV LKALGITEIF IKDANLTGLS DNKEIFLSKA IHKSFLEVNE EGSEAAAVSG MIAISRMAVL YPQVIVDHPF FFLIRNRRTG TILFMGRVMH PETMNTSGHD
Characteristics Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 0.5 μg/mL, corresponding to a specific activity of > 2000 IU/mg.
Purity >95 % as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the ***** nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
Synonyms: Peptidase inhibitor 12, Serpin I1
Molecular Weight 44.7 kDa
UniProt Q99574
Pathways Regulation of Hormone Metabolic Process
Restrictions For Research Use only
Format Lyophilized
Buffer PBS, pH 7.5
Storage -20 °C