产品详情
  • 产品名称:TumorNecrosisFactor(Ligand)Superfamily,Member15(TNFSF15)(Active)Protein

  • 产品型号:
  • 产品厂商:SXBIO
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简单介绍:
TumorNecrosisFactor(Ligand)Superfamily,Member15(TNFSF15)(Active)Protein
详情介绍:
Sequence LKGQEFAPSH QQVYAPLRAD GDKPRAHLTV VRQTPTQHFK NQFPALHWEH ELGLAFTKNR MNYTNKFLLI PESGDYFIYS QVTFRGMTSE CSEIRQAGRP NKPDSITVVI TKVTDSYPEP TQLLMGTKSV CEVGSNWFQP IYLGAMFSLQ EGDKLMVNVS DISLVDYTKE DKTFFGAFLL
Characteristics Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to induce apoptosis using human TF-1 cells is less than 20 ng/mL, corresponding to a specific activity of > 5.0 x 104 IU/mg.
Purity >97 % as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. {ECO:0000269|PubMed:10597252, ECO:0000269|PubMed:11911831, ECO:0000269|PubMed:11923219, ECO:0000269|PubMed:9872942}.
Synonyms: TNF ligand-related molecule 1,
Molecular Weight 20.5 kDa
UniProt O95150
Pathways Positive Regulation of Endopeptidase Activity, Autophagy
Restrictions For Research Use only
Format Lyophilized
Buffer PBS, pH 7.4, with 0.02 % Tween-20
Storage -20 °C