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  • 产品名称：TumorNecrosisFactorReceptorSuperfamily,Member12A(TNFRSF12A)(Active)Protein

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  • 产品厂商：SXBIO
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简单介绍：
TumorNecrosisFactorReceptorSuperfamily,Member12A(TNFRSF12A)(Active)Protein
详情介绍：
Sequence EQAPGTAPCS RGSSWSADLD KCMDCASCRA RPHSDFCLGC AAAPPAPFRL LWP
Characteristics Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by inhibiting TWEAK- dependent proliferation of human umbilical vein endothelial cells (HUVEC) is less than 30 ng/mL, corresponding to a specific activity of ＞ 3.3 x 104 IU/mg, in
Purity >95?% as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. {ECO:0000269|PubMed:11728344}.
Synonyms: Fibroblast growth factor-inducible immediate-early response protein 14, Tweak-receptor, TweakR, CD antigen CD266,
Molecular Weight 5.6 kDa
UniProt Q9NP84
Pathways Apoptosis, Regulation of Cell Size
Restrictions For Research Use only
Format Lyophilized
Buffer PBS,?pH 7.4
Storage -20 °C