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  • 产品名称：Lectin,Galactoside-Binding,Soluble,3(LGALS3)(Active)Protein

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  • 产品厂商：SXBIO
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简单介绍：
Lectin,Galactoside-Binding,Soluble,3(LGALS3)(Active)Protein
详情介绍：
Sequence ADNFSLHDAL SGSGNPNPQG WPGAWGNQPA GAGGYPGASY PGAYPGQAPP GAYPGQAPPG AYPGAPGAYP GAPAPGVYPG PPSGPGAYPS SGQPSATGAY PATGPYGAPA GPLIVPYNLP LPGGVVPRML ITILGTVKPN ANRIALDFQR GNDVAFHFNP RFNENNRRVI VCNTKLDNNW GREERQSVFP FESGKPFKIQ VLVEPDHFKV AVNDAHLLQY NHRVKKLNEI SKLGISGDID LTSASYTMI
Characteristics Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to agglutinate human red blood cells is less than 10 μg/mL.
Purity >98?% as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. {ECO:0000250, ECO:0000269|PubMed:15181153, ECO:0000269|PubMed:19594635, ECO:0000269|PubMed:19616076}.
Synonyms: Gal-3, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein
Molecular Weight 26.0 kDa
UniProt P17931
Pathways RTK Signaling
Restrictions For Research Use only
Format Lyophilized
Buffer 20 mM PB,?pH 7.4, 150?mM NaCl
Storage -20 °C