产品详情
  • 产品名称:PlacentaGrowthFactor(PGF)(Active)Protein

  • 产品型号:
  • 产品厂商:SXBIO
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简单介绍:
PlacentaGrowthFactor(PGF)(Active)Protein
详情介绍:
Sequence LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRPLREKMK PERRRPKGRG KRRREKQRPT DCHLCGDAVP RR
Characteristics Biological Activity: Fully biologically active when compared to standard. The biologically active as determined by its ability to chemoattract human monocytes using a concentration range of 5.0-50 ng/mL.
Purity >97 % as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. {ECO:0000269|PubMed:21215706}.
Synonyms: PlGF,
Molecular Weight 34.6 kDa
UniProt P49763
Pathways VEGFR1 Specific Signals
Restrictions For Research Use only
Format Lyophilized
Buffer PBS, pH 7.4, with 0.02 % Tween-20
Storage -20 °C