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  • 产品名称：PlateletFactor4(PF4)(Active)Protein

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  • 产品厂商：SXBIO
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简单介绍：
PlateletFactor4(PF4)(Active)Protein
详情介绍：
Sequence EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY KKIIKKLLES
Characteristics Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human fibroblasts is in a concentration of 1.0-10 ng/mL.
Purity >97 % as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form. {ECO:0000269|PubMed:7644496}.
Synonyms: PF-4, Iroplact, Oncostatin-A, ,
Molecular Weight 7.8 kDa
UniProt P02776
Research Area Cardiovascular, Atherosclerosis, Innate Immunity
Restrictions For Research Use only
Format Lyophilized
Buffer PBS, pH 7.4
Storage -20 °C