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  • 产品名称：Chemokine(C-CMotif)Ligand21(CCL21)(Active)Protein

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  • 产品厂商：SXBIO
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简单介绍：
Chemokine(C-CMotif)Ligand21(CCL21)(Active)Protein
详情介绍：
Sequence SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCK RTERSQTPKG P
Characteristics Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human lymphocytes is in a concentration range of 10-100 ng/mL.
Purity >97?% as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Synonyms: 6Ckine, Secondary lymphoid-tissue chemokine, SLC, Small-inducible cytokine A21,
Molecular Weight 12.2 kDa
UniProt O00585
Research Area Immunology, Innate Immunity, Chemokines
Pathways Regulation of Actin Filament Polymerization
Restrictions For Research Use only
Format Lyophilized
Buffer PBS,?pH 7.4
Storage -20 °C