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  • 产品名称：FibroblastGrowthFactor21(FGF21)(Active)Protein

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  • 产品厂商：SXBIO
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简单介绍：
FibroblastGrowthFactor21(FGF21)(Active)Protein
详情介绍：
Sequence HPIPDSSPLL QFGGQVRQRY LYTDDAQQTE AHLEIREDGT VGGAADQSPE SLLQLKALKP GVIQILGVKT SRFLCQRPDG ALYGSLHFDP EACSFRELLL EDGYNVYQSE AHGLPLHLPG NKSPHRDPAP RGPARFLPLP GLPPALPEPP GILAPQPPDV GSSDPLSMVG PSQGRSPSYA S
Characteristics Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 μg/mL, corresponding to a specific activity of ＞ 2.0 x 103 IU/mg in the presence of 5 μg/mL o
Purity >96 % as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. {ECO:0000269|PubMed:15902306, ECO:0000269|PubMed:17623664}.
Synonyms: FGF-21,
Molecular Weight 19.4 kDa
UniProt Q9NSA1
Research Area Cancer, Growth Factors, Angiogenesis
Pathways RTK Signaling
Restrictions For Research Use only
Format Lyophilized
Buffer PBS, pH 7.4
Storage -20 °C