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  • 产品名称:anti-HMGB1antibody(High-MobilityGroupBox1)

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  • 产品厂商:SXBIO
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简单介绍:
anti-HMGB1antibody(High-MobilityGroupBox1)
详情介绍:
Immunogen Recombinant human High mobility group protein B1 protein
Isotype IgG
Purification Caprylic Acid Ammonium Sulfate Precipitation
Alternative Name High mobility group protein B1 (HMGB1 Antibody Abstract)
Background DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.
UniProt P09429
Pathways p53 Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration
Application Notes Optimal working concentration should be determinde by the investigator.
Restrictions For Research Use only
Format Liquid
Buffer PBS
Handling Advice Avoid repeated freeze.
Storage -20 °C/-80 °C
Storage Comment Upon delivery aliquot and store at -20 °C or -80 °C.