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  • 产品名称：IGF2(Active)Protein

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  • 产品厂商：SXBIO
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简单介绍：
IGF2(Active)Protein
详情介绍：
Sequence AYRPSETLCG GELVDTLQFV CGDRGFYFSR PASRVSRRSR GIVEECCFRS CDLALLETYC ATPAKSE
Characteristics Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using serum free human MCF-7 cells is less than 2 ng/mL, corresponding to a specific activity of ＞ 5.0 x 105 IU/mg.
Purity >98 % as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development., Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
Synonyms: IGF-II, T3M-11-derived growth factor,
Molecular Weight 7.5 kDa
UniProt P01344
Research Area Growth Factors
Restrictions For Research Use only
Format Lyophilized
Buffer 20 mM Tris-HCl, pH 8.0, 150 mM NaCl, with 0.02 % Tween-20
Storage -20 °C