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Background
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DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. Synonyms: Polydeoxyribonucleotide synthase [NAD(+)],ligA,dnaL, lig, lop, pdeC,b2411, JW2403
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