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  • 产品名称：anti-m7GpppN-mRNAHydrolase(AA1-385)antibody

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  • 产品厂商：SXBIO
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简单介绍：
anti-m7GpppN-mRNAHydrolase(AA1-385)antibody
详情介绍：
Immunogen Recombinant human m7GpppN-mRNA hydrolase (1-385aa)
Isotype IgG
Purification Caprylic Acid Ammonium Sulfate Precipitation purified
Background Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Plays a role in replication-dependent histone mRNA degradation. Has higher activity towards mRNAs that lack a poly(A) tail. Has no activity towards a cap structure lacking an RNA moiety.
UniProt Q8IU60
Research Area Epigenetics, Nuclear Signaling
Restrictions For Research Use only
Format Liquid
Buffer Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C