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  • 产品名称：anti-CHCHD4antibody(Coiled-Coil-Helix-Coiled-Coil-HelixDomainContaining4)(AA1-1

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  • 产品厂商：SXBIO
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简单介绍：
anti-CHCHD4antibody(Coiled-Coil-Helix-Coiled-Coil-HelixDomainContaining4)(AA1-142)
详情介绍：
Immunogen Recombinant human Mitochondrial intermembrane space import and assembly protein 40 protein(1-142aa)
Isotype IgG
Purification Caprylic Acid Ammonium Sulfate Precipitation purified
Alternative Name Mitochondrial Intermembrane Space Import and Assembly Protein 40 (CHCHD4 Antibody Abstract)
Background Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecular disulfide bond and is able to undergo folding in the IMS. Reduced CHCHD4/MIA40 is then reoxidized by GFER/ERV1 via a disulfide relay system.
UniProt Q8N4Q1
Restrictions For Research Use only
Format Liquid
Buffer Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C