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  • 产品名称：anti-HSD17B10antibody(Hydroxysteroid(17-Beta)Dehydrogenase10)(AA2-261)

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  • 产品厂商：SXBIO
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简单介绍：
anti-HSD17B10antibody(Hydroxysteroid(17-Beta)Dehydrogenase10)(AA2-261)
详情介绍：
Immunogen Recombinant human 3-hydroxyacyl-CoA dehydrogenase type-2 protein(2-261aa)
Isotype IgG
Purification Caprylic Acid Ammonium Sulfate Precipitation purified
Alternative Name 3-Hydroxyacyl-CoA Dehydrogenase Type-2 (HSD17B10 Antibody Abstract)
Background Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
UniProt Q99714
Restrictions For Research Use only
Format Liquid
Buffer Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C