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  • 产品名称：anti-Polymerase(RNA)III(DNADirected)PolypeptideK,12.3KDa(POLR3K)(AA1-108)antibo

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  • 产品厂商：SXBIO
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简单介绍：
anti-Polymerase(RNA)III(DNADirected)PolypeptideK,12.3KDa(POLR3K)(AA1-108)antibody
详情介绍：
Immunogen Recombinant human DNA-directed RNA polymerase III subunit RPC10 protein(1-108aa)
Isotype IgG
Purification Caprylic Acid Ammonium Sulfate Precipitation purified
Alternative Name DNA-Directed RNA Polymerase III Subunit RPC10 (POLR3K Antibody Abstract)
Background DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.
UniProt Q9Y2Y1
Restrictions For Research Use only
Format Liquid
Buffer Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C