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产品名称:anti-PTPMT1antibody(ProteinTyrosinePhosphatase,Mitochondrial1)(AA28-201)
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产品厂商:SXBIO
产品文档:
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简单介绍:
anti-PTPMT1antibody(ProteinTyrosinePhosphatase,Mitochondrial1)(AA28-201)
详情介绍:
Product Details anti-PTPMT1
Antibody
Product Details anti-PTPMT1 Antibody
Immunogen
Recombinant human Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 protein(28-201aa)
Isotype
IgG
Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Target Details PTPMT1
Target Details PTPMT1
Alternative Name
Phosphatidylglycerophosphatase and Protein-Tyrosine Phosphatase 1 (PTPMT1 Antibody Abstract)
Background
Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells.
UniProt
Q8WUK0
Pathways
Inositol Metabolic Process
Application Details
Application Details
Restrictions
For Research Use only
Handling
Handling
Format
Liquid
Buffer
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
Preservative
ProClin
Precaution of Use
This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C/-80 °C