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  • 产品名称：TumorNecrosisFactorReceptorSuperfamily,Member14(TNFRSF14)(Active)Protein

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  • 产品厂商：SXBIO
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简单介绍：
TumorNecrosisFactorReceptorSuperfamily,Member14(TNFRSF14)(Active)Protein
详情介绍：
Sequence LPSCKEDEYP VGSECCPKCS PGYRVKEACG ELTGTVCEPC PPGTYIAHLN GLSKCLQCQM CDPAMGLRAS RNCSRTENAV CGCSPGHFCI VQDGDHCAAC RAYATSSPGQ RVQKGGTESQ DTLCQNCPPG TFSPNGTLEE CQHQTKCSWL VTKAGAGTSS SHWVEPKSSD KTHTCPPCPA PEFEGAPSVF LFPPKPKDTL MISRTPEVTC VVVDVSHEDP EVKFNWYVDG VEVHNAKTKP REEQYNSTYR VVSVLTVLHQ DWLNGKEYKC KVSNKALPTP IEKTISKAKG QPREPQVYTL PPSRDELTKN QVSLTCLVKG FYPSDIAVEW ESNGQPENNY KTTPPVLDSD GSFFLYSKLT VDKSRWQQGN VFSCSVMHEA LHNHYTQKSL SLSPGK
Characteristics Biological Activity: Fully biologically active when compared to standard. The biologically active as determined by its ability to inhibit TNF-beta -mediated cytotoxicity using murine L929 cells.
Purity >95 % as determined by SDS-PAGE and HPLC.
Sterility 0.2 μm filtered
Background Relevance: Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells. {ECO:0000269|PubMed:8898196}.
Synonyms: Herpes virus entry mediator A, HveA, Tumor necrosis factor receptor-like 2, TR2, CD antigen CD270
Molecular Weight 58 kDa
UniProt Q92956
Research Area Cancer, Growth Factors, Innate Immunity, Cytokines
Pathways Production of Molecular Mediator of Immune Response
Restrictions For Research Use only
Format Lyophilized
Buffer PBS, pH 7.4, with 3 % Trehalose
Storage -20 °C