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  • 产品名称：anti-CNOT8antibody(CCR4-NOTTranscriptionComplex,Subunit8)(AA1-292)

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  • 产品厂商：SXBIO
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简单介绍：
anti-CNOT8antibody(CCR4-NOTTranscriptionComplex,Subunit8)(AA1-292)
详情介绍：
Immunogen Recombinant human CCR4-NOT transcription complex subunit 8 protein (1-292aa)
Isotype IgG
Purification Antigen Affinity Purified
Alternative Name CCR4-NOT Transcription Complex Subunit 8 (CNOT8 Antibody Abstract)
Background Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.
UniProt Q9UFF9
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C