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  • 产品名称:anti-MinichromosomeMaintenanceComplexComponent6(MCM6)(AA562-821)antibody

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  • 产品厂商:SXBIO
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简单介绍:
anti-MinichromosomeMaintenanceComplexComponent6(MCM6)(AA562-821)antibody
详情介绍:
Immunogen Recombinant human DNA replication licensing factor MCM6 protein(562-821aa)
Isotype IgG
Purification Antigen Affinity Purified
Alternative Name DNA Replication Licensing Factor MCM6 (MCM6 Antibody Abstract)
Background Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP- of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
UniProt Q14566
Pathways DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C