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  • 产品名称：anti-HIP1antibody(HuntingtinInteractingProtein1)(AA410-690)

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  • 产品厂商：SXBIO
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简单介绍：
anti-HIP1antibody(HuntingtinInteractingProtein1)(AA410-690)
详情介绍：
Immunogen Recombinant human Huntingtin-interacting protein 1 protein(410-690aa)
Isotype IgG
Purification Antigen Affinity purified
Alternative Name Huntingtin-Interacting Protein 1 (HIP1 Antibody Abstract)
Background Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. May play a functional role in the cell filament networks. May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors.
UniProt O00291
Pathways Positive Regulation of Endopeptidase Activity
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C