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  • 产品名称：anti-HTRA2antibody(HtrASerinePeptidase2)(AA334-458)

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  • 产品厂商：SXBIO
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简单介绍：
anti-HTRA2antibody(HtrASerinePeptidase2)(AA334-458)
详情介绍：
Immunogen Recombinant human Serine protease HTRA2, mitochondrial protein(334-458aa)
Isotype IgG
Purification Antigen Affinity Purified
Alternative Name Serine Protease HTRA2, Mitochondrial (HTRA2 Antibody Abstract)
Background Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.
UniProt O43464
Pathways Positive Regulation of Endopeptidase Activity
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C