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  • 产品名称：anti-IFT57antibody(IntraflagellarTransport57Homolog(Chlamydomonas))(AA170-429)

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  • 产品厂商：SXBIO
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简单介绍：
anti-IFT57antibody(IntraflagellarTransport57Homolog(Chlamydomonas))(AA170-429)
详情介绍：
Immunogen Recombinant human Intraflagellar transport protein 57 homolog protein (170-429aa)
Isotype IgG
Purification Antigen Affinity Purified
Alternative Name Intraflagellar Transport Protein 57 Homolog (IFT57 Antibody Abstract)
Background Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.
UniProt Q9NWB7
Pathways Hedgehog Signaling, Positive Regulation of Endopeptidase Activity
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C