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  • 产品名称：anti-EZH1antibody(EnhancerofZesteHomolog1(Drosophila))(AA160-280)

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  • 产品厂商：SXBIO
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简单介绍：
anti-EZH1antibody(EnhancerofZesteHomolog1(Drosophila))(AA160-280)
详情介绍：
Immunogen Recombinant human Histone-lysine N-methyltransferase EZH1 protein (160-280aa)
Isotype IgG
Purification Antigen Affinity Purified
Alternative Name Histone-Lysine N-Methyltransferase EZH1 (EZH1 Antibody Abstract)
Background Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
UniProt Q92800
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C