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  • 产品名称：anti-Cullin5antibody(CUL5)(AA1-300)

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  • 产品厂商：SXBIO
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简单介绍：
anti-Cullin5antibody(CUL5)(AA1-300)
详情介绍：
Immunogen Recombinant human Cullin-5 protein(1-300aa)
Isotype IgG
Purification Antigen Affinity Purified
Alternative Name Cullin-5 (CUL5 Antibody Abstract)
Background Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.
UniProt Q93034
Pathways Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C