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  • 产品名称:anti-BCL2/adenovirusE1B19kDaInteractingProtein3-Like(BNIP3L)(AA1-164)antibody

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  • 产品厂商:SXBIO
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简单介绍:
anti-BCL2/adenovirusE1B19kDaInteractingProtein3-Like(BNIP3L)(AA1-164)antibody
详情介绍:
Immunogen Recombinant human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 protein(1-164aa)
Isotype IgG
Purification Antigen Affinity Purified
Alternative Name BCL2/adenovirus E1B 19 kDa Protein-Interacting Protein 3 (BNIP3L Antibody Abstract)
Background Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway.
UniProt Q12983
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C