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  • 产品名称：anti-EmbryonicEctodermDevelopment(EED)(AA1-300)antibody

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  • 产品厂商：SXBIO
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简单介绍：
anti-EmbryonicEctodermDevelopment(EED)(AA1-300)antibody
详情介绍：
Immunogen Recombinant human Polycomb protein EED protein (1-300aa)
Isotype IgG
Purification Antigen Affinity Purified
Alternative Name Polycomb Protein EED (EED Antibody Abstract)
Background Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27', whereas H3 'Lys-27' recognition has the opposite effect, enabling the propagation of this repressive mark. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
UniProt O75530
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C/-80 °C