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  • 产品名称：HepatocyteGrowthFactor(HepapoietinA,ScatterFactor)(HGF)(AA32-728)(Active)Protei

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  • 产品厂商：SXBIO
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简单介绍：
HepatocyteGrowthFactor(HepapoietinA,ScatterFactor)(HGF)(AA32-728)(Active)Protein
详情介绍：
Sequence Gln32 - Ser728, Accession # P14210.2
Characteristics Biological Activity: The ED50, as determined by induction of IL-11 secretion using human Saos-2 cells, is less than 1 ng/mL.
Purity >95 % as determined by SDS-PAGE.
Sterility 0.2 μm filtered
Background Relevance: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. {ECO:0000269|PubMed:15167892, ECO:0000269|PubMed:20624990}.
Synonyms: Hepatopoietin-A, SF,
Molecular Weight 53.7 and 26 kDa
UniProt P14210
Research Area Cancer, Angiogenesis, Hormones, Growth Factors
Pathways RTK Signaling, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
Restrictions For Research Use only
Format Lyophilized
Buffer PBS, pH 7.4
Storage -20 °C