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  • 产品名称：Interleukin-6Receptor(IL6R)(AA20-358)(Active)Protein

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  • 产品厂商：SXBIO
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简单介绍：
Interleukin-6Receptor(IL6R)(AA20-358)(Active)Protein
详情介绍：
Sequence Leu20 - Asp358, Accession # P08887.1
Characteristics Biological Activity: The ED50, as determined by enhancing IL-6 activity using murine M1 cells, is less than 15 ng/mL.
Purity >97?% as determined by SDS-PAGE.
Sterility 0.2 μm filtered
Background Relevance: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis., Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity.
Synonyms: IL-6 receptor subunit alpha, IL-6R-alpha, IL-6RA, IL-6R 1, Membrane glycoprotein 80
Molecular Weight 37.9 kDa
UniProt P08887
Research Area Stem Cells, Hematopoietic Progenitors, Innate Immunity, Cytokines, Immunology
Pathways JAK-STAT Signaling, Autophagy, Growth Factor Binding
Restrictions For Research Use only
Format Lyophilized
Buffer PBS,?pH 7.4.
Storage -20 °C