产品详情
所在位置: 首页> 产品目录> 一抗>
查看大图

  • 产品名称：anti-GATA2antibody(GATABindingProtein2)(AA1-103)

  • 产品型号：
  • 产品厂商：半导体
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
anti-GATA2antibody(GATABindingProtein2)(AA1-103)
详情介绍：
Immunogen GATA2 (AAH18988, 1 a.a. ~ 103 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 K
Clone 1A5
Isotype IgG2b kappa
Specificity GATA2 (AAH18988, 1 a.a. ~ 103 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Purified
Alternative Name GATA2 (GATA2 Antibody Abstract)
Background This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.
Synonyms: MGC2306, NFE1B GATA binding protein 2
Molecular Weight 50396 DA
Gene ID 2624
Research Area Cell Cycle, Transcription Factors, Signaling, Cell Structure
Pathways Stem Cell Maintenance
Application Notes Western blot = 1:500-1000
Comment

Background: This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.
Restrictions For Research Use only
Buffer Phosphate buffered saline, pH 7.2
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-GATA Binding Protein 2 (GATA2) (AA 1-103) antibody (ABIN393992) Immunofluorescence of monoclonal antibody to GATA2 on HeLa cell (antibody concentrati...
Immunohistochemistry (IHC) image for anti-GATA Binding Protein 2 (GATA2) (AA 1-103) antibody (ABIN393992) anti-GATA Binding Protein 2 (GATA2) (AA 1-103) antibody (Image 2)
Background publications Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Shimahara, Yamakawa, Nishikata, Morishita: "Acetylation of lysine 564 adjacent to the C-terminal binding protein-binding motif in EVI1 is crucial for transcriptional activation of GATA2." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 16967-77, 2010 (PubMed).

Dandona, Chen, Fan, Alam, Assogba, Belanger, Williams, Wells, Tang, Ellis, Hazen, McPherson, Roberts, Stewart: "The transcription factor GATA-2 does not associate with angiographic coronary artery disease in the Ottawa Heart Genomics and Cleveland Clinic GeneBank Studies." in: Human genetics, Vol. 127, Issue 1, pp. 101-5, 2010 (PubMed).

Fujiwara, OGeen, Keles, Blahnik, Linnemann, Kang, Choi, Farnham, Bresnick: "Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy." in: Molecular cell, Vol. 36, Issue 4, pp. 667-81, 2009 (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, 2009 (PubMed).