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  • 产品名称：anti-TMPRSS6antibody(TransmembraneProtease,serine6)(AA85-114)

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简单介绍：
anti-TMPRSS6antibody(TransmembraneProtease,serine6)(AA85-114)
详情介绍：
Immunogen This TMPRSS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-114 amino acids from the N-terminal region of human TMPRSS6.
Clone RB39227
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name TMPRSS6 (TMPRSS6 Antibody Abstract)
Background The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver.

Synonyms: TMPRSS6, Transmembrane protease serine 6, Matriptase-2
NCBI Accession NP_705837
UniProt Q8IU80
Pathways Transition Metal Ion Homeostasis
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.45 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Transmembrane Protease, serine 6 (TMPRSS6) (AA 85-114), (N-Term) antibody (ABIN1881891) TMPRSS6 Antibody (N-term) (ABIN1881891) western blot analysis in NCI-H292 cell line l...
Product cited in: Altamura, DAlessio, Selle, Muckenthaler: "A novel TMPRSS6 mutation that prevents protease auto-activation causes IRIDA." in: The Biochemical journal, Vol. 431, Issue 3, pp. 363-71, 2010 (PubMed).

Ucisik-Akkaya, Davis, Do, Morrison, Stemmer, Amadio, Dorak: "Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection." in: Molecular human reproduction, Vol. 16, Issue 10, pp. 770-7, 2010 (PubMed).