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  • 产品名称：anti-HOXA10antibody(HomeoboxA10)(AA252-281)

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  • 产品厂商：半导体
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简单介绍：
anti-HOXA10antibody(HomeoboxA10)(AA252-281)
详情介绍：
Immunogen This Mouse Hoxa10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-281 amino acids from the Central region of mouse Hoxa10.
Clone RB39509
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name Hoxa10 (HOXA10 Antibody Abstract)
Background In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of a cluster on chromosome 6 and encodes a DNA-binding transcription factor that may regulate gene expression, morphogenesis, and differentiation. More specifically, it may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants encoding different isoforms have been described.

Synonyms: Hoxa10, Hox-1.8, Hoxa-10, Homeobox protein Hox-A10, Homeobox protein Hox-1.8
NCBI Accession NP_001116422, NP_032289
UniProt P31310
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Homeobox A10 (HOXA10) (AA 252-281), (Center) antibody (ABIN1881425) Mouse Hoxa10 Antibody (Center) (ABIN1881425) western blot analysis in mouse heart tis...
Product cited in: Gordon, Hassan, Saini, Montecino, van Wijnen, Stein, Stein, Lian: "Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors." in: Molecular and cellular biology, Vol. 30, Issue 14, pp. 3531-41, 2010 (PubMed).

Das: "Regional development of uterine decidualization: molecular signaling by Hoxa-10." in: Molecular reproduction and development, Vol. 77, Issue 5, pp. 387-96, 2010 (PubMed).

Vinagre, Moncaut, Carapuço, Nóvoa, Bom, Mallo: "Evidence for a myotomal Hox/Myf cascade governing nonautonomous control of rib specification within global vertebral domains." in: Developmental cell, Vol. 18, Issue 4, pp. 655-61, 2010 (PubMed).