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  • 产品名称：anti-DIRC2antibody(DisruptedinRenalCarcinoma2)(AA202-229)

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简单介绍：
anti-DIRC2antibody(DisruptedinRenalCarcinoma2)(AA202-229)
详情介绍：
Immunogen This DIRC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-229 amino acids from the Central region of human DIRC2.
Clone RB42515
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name DIRC2 (DIRC2 Antibody Abstract)
Background This gene encodes a membrane-bound protein from the major facilitator superfamily of transporters. Disruption of this gene by translocation has been associated with haplo-insufficiency and renal cell carcinomas. Alternatively spliced transcript variants have been described, but their biological validity has not yet been determined.

Synonyms: DIRC2, Disrupted in renal carcinoma protein 2, Disrupted in renal cancer protein 2
NCBI Accession NP_116228
UniProt Q96SL1
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Disrupted in Renal Carcinoma 2 (DIRC2) (AA 202-229), (Center) antibody (ABIN1881261) DIRC2 Antibody (Center) (ABIN1881261) western blot analysis in 293 cell line lysates ...
Product cited in: Bodmer, Eleveld, Kater-Baats, Janssen, Janssen, Weterman, Schoenmakers, Nickerson, Linehan, Zbar, van Kessel: "Disruption of a novel MFS transporter gene, DIRC2, by a familial renal cell carcinoma-associated t(2;3)(q35;q21)." in: Human molecular genetics, Vol. 11, Issue 6, pp. 641-9, 2002 (PubMed).

Bodmer, Janssen, Jonkers, van den Berg, Dijkhuizen, Debiec-Rychter, Schoenmakers, van Kessel: "Molecular cytogenetic analysis of clustered sporadic and familial renal cell carcinoma-associated 3q13 approximately q22 breakpoints." in: Cancer genetics and cytogenetics, Vol. 136, Issue 2, pp. 95-100, 2002 (PubMed).