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  • 产品名称：anti-DEAD(Asp-Glu-Ala-As)BoxPolypeptide19B(DDX19B)(AA7-36),(N-Term)antibody

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简单介绍：
anti-DEAD(Asp-Glu-Ala-As)BoxPolypeptide19B(DDX19B)(AA7-36),(N-Term)antibody
详情介绍：
Immunogen This DDX19B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human DDX19B.
Clone RB41830
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name DDX19B (DDX19B Antibody Abstract)
Background DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms: DDX19B, DBP5, DDX19, TDBP, ATP-dependent RNA helicase DDX19B, DEAD box RNA helicase DEAD5, DEAD box protein 19B
NCBI Accession NP_001014449, NP_009173, NP_001244102, NP_001014451, NP_001244101, NP_001244103
UniProt Q9UMR2
Research Area Signaling
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-DEAD (Asp-Glu-Ala-As) Box Polypeptide 19B (DDX19B) (AA 7-36), (N-Term) antibody (ABIN1881254) DDX19B Antibody (N-term) (ABIN1881254) western blot analysis in NCI-H460 cell line ly...
Product cited in: Collins, Karlberg, Lehtiö, Schütz, van den Berg, Dahlgren, Hammarström, Weigelt, Schüler: "The DEXD/H-box RNA helicase DDX19 is regulated by an {alpha}-helical switch." in: The Journal of biological chemistry, Vol. 284, Issue 16, pp. 10296-300, 2009 (PubMed).

von Moeller, Basquin, Conti: "The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner." in: Nature structural & molecular biology, Vol. 16, Issue 3, pp. 247-54, 2009 (PubMed).

Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).