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  • 产品名称：anti-GlutamateDehydrogenase2(GLUD2)(AA75-103),(N-Term)antibody

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简单介绍：
anti-GlutamateDehydrogenase2(GLUD2)(AA75-103),(N-Term)antibody
详情介绍：
Immunogen This GLUD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-103 amino acids from the N-terminal region of human GLUD2.
Clone RB42527
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name GLUD2 (GLUD2 Antibody Abstract)
Background The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.

Synonyms: GLUD2, GLUDP1, Glutamate dehydrogenase 2, mitochondrial
NCBI Accession NP_036216
UniProt P49448
Research Area Metabolism, Amino Acids
Pathways Synaptic Membrane
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Glutamate Dehydrogenase 2 (GLUD2) (AA 75-103), (N-Term) antibody (ABIN1881376) GLUD2 Antibody (N-term) (ABIN1881376) western blot analysis in HepG2 cell line lysate...
Product cited in: Spanaki, Zaganas, Kleopa, Plaitakis: "Human GLUD2 glutamate dehydrogenase is expressed in neural and testicular supporting cells." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 16748-56, 2010 (PubMed).

Plaitakis, Latsoudis, Kanavouras, Ritz, Bronstein, Skoula, Mastorodemos, Papapetropoulos, Borompokas, Zaganas, Xiromerisiou, Hadjigeorgiou, Spanaki: "Gain-of-function variant in GLUD2 glutamate dehydrogenase modifies Parkinson's disease onset." in: European journal of human genetics : EJHG, Vol. 18, Issue 3, pp. 336-41, 2010 (PubMed).