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  • 产品名称：anti-ChlorideChannel5antibody(CLCN5)(AA15-41)

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简单介绍：
anti-ChlorideChannel5antibody(CLCN5)(AA15-41)
详情介绍：
Immunogen This CLCN5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-41 amino acids from the N-terminal region of human CLCN5.
Clone RB42009
Predicted Reactivity Mouse (Murine),Pig (Porcine),Rat (Rattus),Rabbit
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name CLCN5 (CLCN5 Antibody Abstract)
Background This gene encodes a member of the ClC family of chloride ion channels and ion transporters. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Synonyms: CLCN5, CLCK2, H(+)/Cl(-) exchange transporter 5, Chloride channel protein 5, Chloride transporter ClC-5
NCBI Accession NP_000075, NP_001269092, NP_001121370, NP_001121371
UniProt P51795
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.4 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Chloride Channel 5 (CLCN5) (AA 15-41), (N-Term) antibody (ABIN1881207) CLCN5 Antibody (N-term) (ABIN1881207) western blot analysis in K562 cell line lysates...
Product cited in: Smith, Lippiat: "Voltage-dependent charge movement associated with activation of the CLC-5 2Cl-/1H+ exchanger." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 10, pp. 3696-705, 2010 (PubMed).

Wellhauser, DAntonio, Bear: "ClC transporters: discoveries and challenges in defining the mechanisms underlying function and regulation of ClC-5." in: Pflügers Archiv : European journal of physiology, Vol. 460, Issue 2, pp. 543-57, 2010 (PubMed).

Picollo, Malvezzi, Accardi: "Proton block of the CLC-5 Cl-/H+ exchanger." in: The Journal of general physiology, Vol. 135, Issue 6, pp. 653-9, 2010 (PubMed).

White: "On the position and value of those Lesions of the Brain which cause a rise of Temperature." in: The Journal of physiology, Vol. 12, Issue 3, pp. 233-298.3, 2007 (PubMed).