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  • 产品名称:anti-CD3eMolecule,epsilonAssociatedProtein(CD3EAP)(AA54-81),(N-Term)antibody

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简单介绍:
anti-CD3eMolecule,epsilonAssociatedProtein(CD3EAP)(AA54-81),(N-Term)antibody
详情介绍:
Immunogen This CD3EAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-81 amino acids from the N-terminal region of human CD3EAP.
Clone RB41983
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name CD3EAP (CD3EAP Antibody Abstract)
Background DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Isoform 1 is involved in UBTF-activated transcription, presumably at a step following PIC formation. Isoform 2 has been described as a component of preformed T-cell receptor (TCR) complex.

Synonyms: CD3EAP, ASE1, CAST, PAF49, DNA-directed RNA polymerase I subunit RPA34, A34.5, Antisense to ERCC-1 protein, CD3-epsilon-associated protein, RNA polymerase I-associated factor PAF49
NCBI Accession NP_036231
UniProt O15446
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (AA 54-81), (N-Term) antibody (ABIN1881185) CD3EAP Antibody (N-term) (ABIN1881185) western blot analysis in Hela cell line lysate...
Product cited in: Guey, García-Closas, Murta-Nascimento, Lloreta, Palencia, Kogevinas, Rothman, Vellalta, Calle, Marenne, Tardón, Carrato, García-Closas, Serra, Silverman, Chanock, Real, Malats: "Genetic susceptibility to distinct bladder cancer subphenotypes." in: European urology, Vol. 57, Issue 2, pp. 283-92, 2010 (PubMed).

Vangsted, Klausen, Gimsing, Andersen, Abildgaard, Gregersen, Vogel: "A polymorphism in NFKB1 is associated with improved effect of interferon-{alpha} maintenance treatment of patients with multiple myeloma after high-dose treatment with stem cell support." in: Haematologica, Vol. 94, Issue 9, pp. 1274-81, 2009 (PubMed).

Nissen, Vogel, Nexø: "Association of a single nucleotide polymorphic variation in the human chromosome 19q13.3 with drug responses in the NCI60 cell lines." in: Anti-cancer drugs, Vol. 20, Issue 3, pp. 174-8, 2009 (PubMed).

Hosgood, Zhang, Shen, Berndt, Vermeulen, Li, Yin, Yeager, Yuenger, Rothman, Chanock, Smith, Lan: "Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity." in: Occupational and environmental medicine, Vol. 66, Issue 12, pp. 848-53, 2009 (PubMed).