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  • 产品名称：anti-ST6GAL1antibody(ST6beta-Galactosamidealpha-2,6-Sialyltranferase1)(AA178-20

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简单介绍：
anti-ST6GAL1antibody(ST6beta-Galactosamidealpha-2,6-Sialyltranferase1)(AA178-206)
详情介绍：
Immunogen This ST6GAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-206 amino acids from the Central region of human ST6GAL1.
Clone RB41682
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name ST6GAL1 (ST6GAL1 Antibody Abstract)
Background This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described.

Synonyms: ST6GAL1, SIAT1, Beta-galactoside alpha-2,6-sialyltransferase 1, B-cell antigen CD75, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6Gal I, Sialyltransferase 1
NCBI Accession NP_775323, NP_775324, NP_003023
UniProt P15907
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.48 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-ST6 beta-Galactosamide alpha-2,6-Sialyltranferase 1 (ST6GAL1) (AA 178-206), (Center) antibody (ABIN1881841) ST6GAL1 Antibody (Center) (ABIN1881841) western blot analysis in HepG2 cell line lysa...
Product cited in: Mondal, Chandra, Mandal: "Elevated mRNA level of hST6Gal I and hST3Gal V positively correlates with the high risk of pediatric acute leukemia." in: Leukemia research, Vol. 34, Issue 4, pp. 463-70, 2010 (PubMed).

Lee, Park, Lee: "Adhesion of ST6Gal I-mediated human colon cancer cells to fibronectin contributes to cell survival by integrin beta1-mediated paxillin and AKT activation." in: Oncology reports, Vol. 23, Issue 3, pp. 757-61, 2010 (PubMed).

Daly, Donaldson, Bhatnagar, Shen, Peer, Floratos, Daly, Goldstein, John, Nelson, Graham, Park, Dillon, Bernal, Cordell, Pirmohamed, Aithal, Day: "HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin." in: Nature genetics, Vol. 41, Issue 7, pp. 816-9, 2009 (PubMed).

Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, 1996 (PubMed).