anti-Msx2(AA191-222),(C-Term)antibody 抗体网

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产品名称：anti-Msx2(AA191-222),(C-Term)antibody
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产品厂商：半导体
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简单介绍：

anti-Msx2(AA191-222),(C-Term)antibody

详情介绍：

Product details
Product details
Immunogen	This Msx2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-222 amino acids from the C-terminal region of human Msx2.
Clone	RB10531
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Target details
Target details
Background	This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2. Synonyms: Homeobox protein MSX-2, Hox-8, MSX2, HOX8
NCBI Accession	NP_002440
UniProt	P35548

Application Details
Application Details
Application Notes	WB: 1:1000,IHC (p): 1:10-50
Restrictions	For Research Use only

Handling
Handling
Format	Liquid
Concentration	0.39 mg/mL
Buffer	Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative	Sodium azide
Precaution of Use	WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Images
Images
Supplier Images	Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with Msx2 ... Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with Msx2 ... Images for product: anti-Msx2 (AA 191-222), (C-Term) antibody Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with Msx2 Antibody (C-term) (ABIN1881555), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with Msx2 Antibody (C-term) (ABIN1881555), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated.

References
References
Product cited in:	Shao, Aly, Lai, Cheng, Cai, Huang, Behrmann, Towler: "Vascular Bmp Msx2 Wnt signaling and oxidative stress in arterial calcification." in: Annals of the New York Academy of Sciences, Vol. 1117, pp. 40-50, 2007 (PubMed).