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  • 产品名称：anti-YWHAZantibody(tyrosine3-Monooxygenase/tryptophan5-MonooxygenaseActivationP

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简单介绍：
anti-YWHAZantibody(tyrosine3-Monooxygenase/tryptophan5-MonooxygenaseActivationProtein,zetaPolypeptide)
详情介绍：
Immunogen This YWHAZ antibody is generated from a mouse immunized with a recombinant protein from human YWHAZ.
Clone 1314CT423-108-153-173-140
Isotype IgG2b, kappa
Predicted Reactivity Cow (Bovine)
Purification This antibody is purified through a protein G column, followed by dialysis against PBS. Purified
Alternative Name YWHAZ (YWHAZ Antibody Abstract)
Background Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.

Synonyms: 14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1, YWHAZ
UniProt P63104
Pathways Apoptosis, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, zeta Polypeptide (YWHAZ) antibody (ABIN1882058) Western blot analysis of lysates from A431, HepG2, mouse NIH/3T3, rat PC-12 and C6 ce...
Background publications Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Gevaert, Goethals, Martens, Van Damme, Staes, Thomas, Vandekerckhove: "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides." in: Nature biotechnology, Vol. 21, Issue 5, pp. 566-9, 2003 (PubMed).

Product cited in: Seluja, Elias, Pietromonaco: "Two unique 5' untranslated regions in mRNAs encoding human 14-3-3 zeta: differential expression in hemopoietic cells." in: Biochimica et biophysica acta, Vol. 1395, Issue 3, pp. 281-7, 1998 (PubMed).

Zupan, Steffens, Berry, Landt, Gross: "Cloning and expression of a human 14-3-3 protein mediating phospholipolysis. Identification of an arachidonoyl-enzyme intermediate during catalysis." in: The Journal of biological chemistry, Vol. 267, Issue 13, pp. 8707-10, 1992 (PubMed).