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  • 产品名称：anti-TUBG1antibody(Tubulin,gamma1)(AA23-51)

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简单介绍：
anti-TUBG1antibody(Tubulin,gamma1)(AA23-51)
详情介绍：
Immunogen This TUBG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-51 amino acids from the N-terminal region of human TUBG1.
Clone RB40908
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus),Xenopus laevis
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name TUBG1 (TUBG1 Antibody Abstract)
Background This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7.

Synonyms: TUBG1, TUBG, Tubulin gamma-1 chain, Gamma-1-tubulin, Gamma-tubulin complex component 1
NCBI Accession NP_001061
UniProt P23258
Pathways Microtubule Dynamics, M Phase
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Tubulin, gamma 1 (TUBG1) (AA 23-51), (N-Term) antibody (ABIN1881959) TUBG1 Antibody (N-term) (ABIN1881959) western blot analysis in HepG2 cell line lysate...
Product cited in: Couch, Wang, Bamlet, de Andrade, Petersen, McWilliams: "Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 1, pp. 251-7, 2010 (PubMed).

Alvarado-Kristensson, Rodríguez, Silió, Valpuesta, Carrera: "SADB phosphorylation of gamma-tubulin regulates centrosome duplication." in: Nature cell biology, Vol. 11, Issue 9, pp. 1081-92, 2009 (PubMed).

Zhang, Chen, Feng, Hou, Yang, Liu, Jiang, Zhang: "Sequential phosphorylation of Nedd1 by Cdk1 and Plk1 is required for targeting of the gammaTuRC to the centrosome." in: Journal of cell science, Vol. 122, Issue Pt 13, pp. 2240-51, 2009 (PubMed).