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  • 产品名称：anti-USP25antibody(UbiquitinSpecificPeptidase25)

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简单介绍：
anti-USP25antibody(UbiquitinSpecificPeptidase25)
详情介绍：
Immunogen This USP25 antibody is generated from a mouse immunized with a recombinant protein from human USP25.
Clone 1277CT376-106-171
Isotype IgG1, kappa
Purification This antibody is purified through a protein G column, followed by dialysis against PBS. Purified
Alternative Name USP25 (USP25 Antibody Abstract)
Background Deubiquitinating enzyme that hydrolyzes ubiquitin moieties conjugated to substrates and thus, functions to process newly synthesized Ubiquitin, to recycle ubiquitin molecules or to edit polyubiquitin chains and prevents proteasomal degradation of substrates. Hydrolyzes both 'Lys-48'- and 'Lys-63'-linked tetraubiquitin chains.

Synonyms: Ubiquitin carboxyl-terminal hydrolase 25, Deubiquitinating enzyme 25, USP on chromosome 21, Ubiquitin thioesterase 25, Ubiquitin-specific-processing protease 25, USP25, USP21
UniProt Q9UHP3
Research Area Proteolysis / Ubiquitin
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Ubiquitin Specific Peptidase 25 (USP25) antibody (ABIN1882057) Western blot analysis of lysate from Daudi cell line, using USP25 Antibody (ABIN18820...
Background publications Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Product cited in: Groet, Ives, Jones, Danton, Flomen, Sheer, Hrascan, Pavelic, Nizetic: "Narrowing of the region of allelic loss in 21q11-21 in squamous non-small cell lung carcinoma and cloning of a novel ubiquitin-specific protease gene from the deleted segment." in: Genes, chromosomes & cancer, Vol. 27, Issue 2, pp. 153-61, 2000 (PubMed).

Valero, Marfany, González-Angulo, González-González, Puelles, Gonzàlez-Duarte: "USP25, a novel gene encoding a deubiquitinating enzyme, is located in the gene-poor region 21q11.2." in: Genomics, Vol. 62, Issue 3, pp. 395-405, 2000 (PubMed).