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  • 产品名称:anti-Prohibitinantibody(PHB)(AA1-205)

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简单介绍:
anti-Prohibitinantibody(PHB)(AA1-205)
详情介绍:
Immunogen This antibody is generated from a mice immunized with a recombinant protein between 1-205 amino acids from human.
Clone 1215CT487-109-106
Isotype IgG2b, kappa
Purification This antibody is purified through a protein G column, followed by dialysis against PBS. Purified
Alternative Name PHB (PHB Antibody Abstract)
Background Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.

Synonyms: Prohibitin, PHB
UniProt P35232
Pathways Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Prohibitin (PHB) (AA 1-205) antibody (ABIN1882051) Western blot analysis of lysates from 293,MCF-7,HepG2,mouse NIH/3T3 cell line and rat...
Product cited in: Sato, Sakamoto, Takita, Saito, Okui, Nakamura: "The human prohibitin (PHB) gene family and its somatic mutations in human tumors." in: Genomics, Vol. 17, Issue 3, pp. 762-4, 1993 (PubMed).

Background publications Sato, Saito, Swensen, Olifant, Wood, Danner, Sakamoto, Takita, Kasumi, Miki: "The human prohibitin gene located on chromosome 17q21 is mutated in sporadic breast cancer." in: Cancer research, Vol. 52, Issue 6, pp. 1643-6, 1992 (PubMed).