anti-AldehydeDehydrogenase2Family(Mitochondrial)(ALDH2)antibody 抗体网

产品详情

所在位置: 首页> 产品目录> 一抗>

查看大图

产品名称：anti-AldehydeDehydrogenase2Family(Mitochondrial)(ALDH2)antibody
产品型号：
产品厂商：半导体
产品文档：

你添加了1件商品查看购物车

简单介绍：

anti-AldehydeDehydrogenase2Family(Mitochondrial)(ALDH2)antibody

详情介绍：

Product details
Product details
Immunogen	This ALDH2 antibody is generated from rabbits immunized with human ALDH2 recombinant protein.
Clone	RB23145
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Target details
Target details
Alternative Name	ALDH2 (ALDH2 Antibody Abstract)
Background	ALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme. Synonyms: ALDH2, ALDM, Aldehyde dehydrogenase, mitochondrial, ALDH class 2, ALDH-E2, ALDHI
NCBI Accession	NP_000681, NP_001191818
UniProt	P05091
Research Area	Cardiovascular, Atherosclerosis, Metabolism, Organelles

Application Details
Application Details
Application Notes	WB: 1:1000,IHC (p): 1:50-100,FACS: 1:10-50
Restrictions	For Research Use only

Handling
Handling
Format	Liquid
Concentration	0.33 mg/mL
Buffer	Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative	Sodium azide
Precaution of Use	WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Images
Images
Supplier Images	ALDH2 Antibody (ABIN1881053) flow cytometry analysis of MDA-MB231 cells (bottom histo... ALDH2 Antibody (ABIN1881053) flow cytometry analysis of MDA-MB231 cells (bottom histo... ALDH2 Antibody (ABIN1881053) flow cytometry analysis of MDA-MB231 cells (bottom histo... Images for product: anti-Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2) antibody ALDH2 Antibody (ABIN1881053) flow cytometry analysis of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. ALDH2 Antibody (ABIN1881053) flow cytometry analysis of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. ALDH2 Antibody (ABIN1881053) flow cytometry analysis of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

References
References
Product cited in:	Guo, Wang, Liu, Chen, Qi, Guo: "Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males." in: World journal of gastroenterology : WJG, Vol. 14, Issue 9, pp. 1444-9, 2008 (PubMed). Chen, Smith, Harbord, Lewis: "Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach." in: PLoS medicine, Vol. 5, Issue 3, pp. e52, 2008 (PubMed). Teeguarden, Bogdanffy, Covington, Tan, Jarabek: "A PBPK model for evaluating the impact of aldehyde dehydrogenase polymorphisms on comparative rat and human nasal tissue acetaldehyde dosimetry." in: Inhalation toxicology, Vol. 20, Issue 4, pp. 375-90, 2008 (PubMed).