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  • 产品名称：anti-PTGER4antibody(ProstaglandinEReceptor4(SubtypeEP4))(AA242-269)

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简单介绍：
anti-PTGER4antibody(ProstaglandinEReceptor4(SubtypeEP4))(AA242-269)
详情介绍：
Immunogen This PTGER4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-269 amino acids from the Central region of human PTGER4.
Clone RB44208
Predicted Reactivity Cow (Bovine),Rat (Rattus),Rabbit
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name PTGER4 (PTGER4 Antibody Abstract)
Background Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

Synonyms: PTGER4,PTGER2, Prostaglandin E2 receptor EP4 subtype, Prostaglandin E2 receptor EP4 subtype, Prostanoid EP4 receptor
NCBI Accession NP_000949
UniProt P35408
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Prostaglandin E Receptor 4 (Subtype EP4) (PTGER4) (AA 242-269), (Center) antibody (ABIN1881704) PTGER4 Antibody (Center) (ABIN1881704) western blot analysis in HL-60,K562 cell line ...
Product cited in: Mori, Tanaka, Kotani, Miyaoka, Sando, Muro, Sasaki, Nakagawa, Ogawa, Usui, Ozaki, Ichikawa, Narumiya, Nakao: "Gene expression of the human prostaglandin E receptor EP4 subtype: differential regulation in monocytoid and lymphoid lineage cells by phorbol ester." in: Journal of molecular medicine (Berlin, Germany), Vol. 74, Issue 6, pp. 333-6, 1996 (PubMed).

Foord, Marks, Stolz, Bufflier, Fraser, Lee: "The structure of the prostaglandin EP4 receptor gene and related pseudogenes." in: Genomics, Vol. 35, Issue 1, pp. 182-8, 1996 (PubMed).

Bastien, Sawyer, Grygorczyk, Metters, Adam: "Cloning, functional expression, and characterization of the human prostaglandin E2 receptor EP2 subtype." in: The Journal of biological chemistry, Vol. 269, Issue 16, pp. 11873-7, 1994 (PubMed).

An, Yang, Xia, Goetzl: "Cloning and expression of the EP2 subtype of human receptors for prostaglandin E2." in: Biochemical and biophysical research communications, Vol. 197, Issue 1, pp. 263-70, 1994 (PubMed).