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  • 产品名称：anti-CathepsinDantibody(CTSD)

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简单介绍：
anti-CathepsinDantibody(CTSD)
详情介绍：
Immunogen Purified His-tagged CTSD protein was used to produced this monoclonal antibody.
Clone 892CT11-1-1
Isotype IgG1
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name CTSD (CTSD Antibody Abstract)
Background Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

Synonyms: CTSD,CPSD, Cathepsin D, Cathepsin D light chain, Cathepsin D heavy chain
NCBI Accession NP_001900
UniProt P07339
Pathways Peptide Hormone Metabolism
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Cathepsin D (CTSD) antibody (ABIN1882228) CTSD Antibody (ABIN1882228) western blot analysis in MCF-7,U251,HepG2 cell line lysat...
Product cited in: Burkard, Planyavsky, Kaupe, Breitwieser, Bürckstümmer, Bennett, Superti-Furga, Colinge: "Initial characterization of the human central proteome." in: BMC systems biology, Vol. 5, pp. 17, 2011 (PubMed).

Redecker, Heckendorf, Grosch, Mersmann, Hasilik: "Molecular organization of the human cathepsin D gene." in: DNA and cell biology, Vol. 10, Issue 6, pp. 423-31, 1991 (PubMed).

Westley, May: "Oestrogen regulates cathepsin D mRNA levels in oestrogen responsive human breast cancer cells." in: Nucleic acids research, Vol. 15, Issue 9, pp. 3773-86, 1987 (PubMed).

Faust, Kornfeld, Chirgwin: "Cloning and sequence analysis of cDNA for human cathepsin D." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 82, Issue 15, pp. 4910-4, 1985 (PubMed).