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  • 产品名称：anti-Polymerase(RNA)II(DNADirected)PolypeptideC,33kDa(POLR2C)(AA200-228),(C-Ter

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简单介绍：
anti-Polymerase(RNA)II(DNADirected)PolypeptideC,33kDa(POLR2C)(AA200-228),(C-Term)antibody
详情介绍：
Immunogen This POLR2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-228 amino acids from the C-terminal region of human POLR2C.
Predicted Reactivity Cow (Bovine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Alternative Name POLR2C (POLR2C Antibody Abstract)
Background DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft (By similarity).

Synonyms: POLR2C,DNA-directed RNA polymerase II subunit RPB3
NCBI Accession NP_116558
UniProt P19387
Research Area Chromatin and Nuclear Signaling, Transcription Factors, DNA/RNA
Pathways Regulatory RNA Pathways
Application Notes WB: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.37 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Supplier Images
Western Blotting (WB) image for anti-Polymerase (RNA) II (DNA Directed) Polypeptide C, 33kDa (POLR2C) (AA 200-228), (C-Term) antibody (ABIN1881670) POLR2C Antibody (C-term) (ABIN1881670) western blot analysis in Hela,U251 cell line a...
Product cited in: Dammann, Pfeifer: "Cloning and characterization of the human RNA polymerase I subunit hRPA40." in: Biochimica et biophysica acta, Vol. 1396, Issue 2, pp. 153-7, 1998 (PubMed).

Pati, Weissman: "The amino acid sequence of the human RNA polymerase II 33-kDa subunit hRPB 33 is highly conserved among eukaryotes." in: The Journal of biological chemistry, Vol. 265, Issue 15, pp. 8400-3, 1990 (PubMed).